Translational Bioimaging Resource

RII Core Facilities Pilot Program - May 3, 2023 Deadline

Date of publication

The RII Core Facilities Pilot Program is designed to support three key types of activity within the RII-managed core facilities. Each CFPP proposal will be evaluated on scientific merit and feasibility, and should focus on one or more of the following activity types:

  1. The development of new methods or techniques that would extend the standard operating procedures and capabilities of RII-managed core facilities and potentially impact multiple UA researchers.
  2. The acquisition of preliminary data needed for extramural proposals. Successful projects will result in at least one new extramural research proposal.
  3. The technical training of students conducting research under existing extramural funding. Proposals to train students from traditionally marginalized groups will be given funding priority.

Most awards will be capped at approximately $10,000, although well-justified projects may be awarded funding above this level. It is required that CFPP proposals and their budgets be developed with the assistance of the relevant core facility manager(s). Proposals are due May 3, 2023 by 5pm. List of eligible facilities:

  1. Analytical and Biological Mass Spectrometry
  2. Flow Cytometry and Human Immune Monitoring Shared Resource (BD LSR, BD, FACSARIA, BD Canto)
  3. Functional Genomics Core
  4. Imaging Cores - Electron
  5. Imaging Cores - Optical
  6. Machining and Welding Center
  7. Micro/Nano Fabrication Center
  8. Translational Bioimaging Resource
  9. University of Arizona Genetics Core
  10. BIO5 Genetically Engineered Mouse Models (GEMM) Core
  11. Arizona Genomics Institute

Application and Full Details

Related Facility
corebusiness
massspec
flowcytometry
fgc
electronimaging
opticalimaging
machineshop
nanofab
tbir
azgc

Photoacoustic Imaging workshop (Sept 14-15, 2022)

Date of publication

Visualsonics will be offering a free virtual workshop on photoacoustic imaging September 14-15 from 10am-12:30pm (local time). This is an excellent opportunity for researchers to get additional/advanced training on the PA imaging technology that we have at the University of Arizona (Translational Imaging Resource located in BSRL).

For the training agenda and to register: https://secure.visualsonics.com/SummerNASA

What is Photoacoustic imaging? "PAI combines the advantages of optical imaging and ultrasound imaging, which can effectively image the structure and function of biological tissues. It provides an important means for studying the morphological structure, physiological characteristics, pathological characteristics, and metabolic function of biological tissues." (Molecular Imaging: https://www.sciencedirect.com/book/9780128163863/molecular-imaging)

Contact
Russell Witte
Related Facility
tbir

VisualSonics Vevo 2100

The VisualSonics Vevo 2100 is a high-resolution small-animal ultrasound imaging system with axial resolution as low as 30 microns.

Equipment

Quantitative Digital Histology

Through a partnership with the University of Arizona Cancer Center the TBIR offers access to Definiens Tissue Studio 4.2 for biomarker and morphological profiling in histological images. Tissue Studio is an easy to use, robust, and powerful tool to automatically detect regions of interest based on user-defined criteria. It can distinguish cells and sub-cellular objects within target regions, and determine morphology and expression profiles per individual cell or cell compartment. It is compatible with brightfield or immunofluorescence images and whole tissue slides or tissue microarrays. Tissue Studio is compatible with most major file formats including Aperio (.svs), Hamamatsu (.ndpi), Leica (.scn), Roche Ventana (.bif), Zeiss (.czi), and TIFF.

Service

Bioluminescence and Fluorescence Imaging

Through a partnership with the University of Arizona Cancer Center, the TBIR provides a Spectral Instruments Imaging Lago, which has powerful multi-modality imaging capabilities in an advanced, user-friendly system. The turn-key system offers bioluminescence and fluorescence imaging. The high performance 2048x2048 air-cooled CCD camera provides high sensitivity with low background noise for accurate quantitative analysis. The Lago has 14 excitation wavelengths ranging from 360-805 nm and 20 emission filters ranging from 490-870 nm. The system has a field-of-view ranging from 6x6 cm up to 25x25 cm. These dynamic filter combinations can support a wide range of applications ranging from well-plate imaging to small animal imaging. Bioluminescence imaging of reporter genes such as luciferase and green fluorescent protein are easily accomplished with this scanner, and imaging of exogenous fluorescent agents can also be performed. The Lago incorporates a heated imaging platform and built-in isoflurane gas anesthesia.

Service
Contact
Brenda Baggett
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