BRUKER SPATIAL BIOLOGY | LUNCH & LEARN

Integrated Multiomics with Bruker — From Bulk Gene Expression to Spatial Multiomic Insights

In Collaboration with the University of Arizona Molecular Clinical Core 

Thursday, April 9^th 12:30–2:00 PM MST

University of Arizona Medical Research Building Room 102

REGISTER HERE: Lunch & Learn | University of Arizona

Please Join Us

Join us for an engaging seminar spotlighting the nCounter® Analysis System and its newly expanded bulk Multiomic capabilities. Learn how researchers can now measure RNA and protein from the same sample to gain deeper biological insight. The session will also feature an overview of Bruker Spatial Biology’s spatial portfolio, highlighting how these technologies are used, what they enable, and recent advances across the lineup. Guest speaker presentations will wrap up the session, followed by Q&A. Complimentary lunch and deserts will be provided! 

The University of Arizona scientific community is invited to join us for a lunchtime session featuring a focused deep dive into our suite of bulk and spatial multiomic technologies. During this session, we’ll provide high-level overviews of the platforms, alongside guest speaker presentations showcasing how researchers are applying these tools in their own studies. We’ll also share how to access these technologies on campus for your own work, including the recently installed nCounter PRO System, along with updates across the portfolio that expand capabilities and support deeper biological insights.

Technologies at a Glance

• Get results in under 24 hours with just 15 minutes of hands-on time—multiplex up to 800 targets using the nCounter® Analysis System's direct detection technology. Now, the platform is evolving beyond bulk gene expression with new bulk multiomics capabilities, enabling RNA and protein analysis from the same FFPE sample.
• The GeoMx® Digital Spatial Profiler is the only spatial biology platform that non-destructively profiles expression of the whole transcriptome and 1,200+ proteins from a single FFPE or fresh frozen tissue section.
• The CosMx® Spatial Molecular Imager is the only single-cell spatial platform that enables whole transcriptome RNA analysis paired with high-plex protein detection—up to 76 proteins). From cell atlasing to signaling pathway analysis, gain deep biological context and subcellular resolution—all from one experiment.
• CellScape™ Precise Spatial Proteomics offers end-to-end multiplexed spatial proteomics and single-cell analysis with advanced imaging, automated fluidics, and flexible assay design for any species to accelerate research from discovery to translation.

Agenda Overview

The ORP Core Facilities Pilot Program is designed to support three key types of activity within the ORP-managed core facilities. Each CFPP proposal will be evaluated on scientific merit and feasibility, and should focus on one or more of the following activity types:

1. The development of new methods or techniques that would extend the standard operating procedures and capabilities of ORP-managed core facilities and potentially impact multiple UA researchers. Successful projects will result in new methods or techniques which will be disseminated to the UA research community via the core’s website, and be incorporated into the core’s standard operating procedures and capabilities.
2. The acquisition of preliminary data needed for extramural proposals. Successful projects will result in at least one new extramural research proposal. PIs must note the specific extramural funding opportunity announcement for which they plan to submit and their anticipated submission date along with their CFPP application. A full justification of the anticipated studies is required.
3. The technical training of students conducting research under existing extramural funding. Successful projects will result in student researchers with the technical skills to operate equipment safely, efficiently and independently within the core facility(ies). PIs should note the student(s) to be trained, the core(s) in which they will be trained, the equipment on which they are to be trained, and the funding source under which the student’s research project is funded. Proposals to train students from traditionally marginalized groups will be given funding priority.

For additional information and to apply, see Arizona Cultivate.

The ORP Core Facilities Pilot Program is designed to support three key types of activity within the ORP-managed core facilities. Each CFPP proposal will be evaluated on scientific merit and feasibility, and should focus on one or more of the following activity types:

1. The development of new methods or techniques that would extend the standard operating procedures and capabilities of ORP-managed core facilities and potentially impact multiple UA researchers. Successful projects will result in new methods or techniques which will be disseminated to the UA research community via the core’s website, and be incorporated into the core’s standard operating procedures and capabilities.
2. The acquisition of preliminary data needed for extramural proposals. Successful projects will result in at least one new extramural research proposal. PIs must note the specific extramural funding opportunity announcement for which they plan to submit and their anticipated submission date along with their CFPP application. A full justification of the anticipated studies is required.
3. The technical training of students conducting research under existing extramural funding. Successful projects will result in student researchers with the technical skills to operate equipment safely, efficiently and independently within the core facility(ies). PIs should note the student(s) to be trained, the core(s) in which they will be trained, the equipment on which they are to be trained, and the funding source under which the student’s research project is funded. Proposals to train students from traditionally marginalized groups will be given funding priority.

For additional information and to apply, see Arizona Cultivate.

The ORP Core Facilities Pilot Program is designed to support three key types of activity within the ORP-managed core facilities. Each CFPP proposal will be evaluated on scientific merit and feasibility, and should focus on one or more of the following activity types:

1. The development of new methods or techniques that would extend the standard operating procedures and capabilities of ORP-managed core facilities and potentially impact multiple UA researchers. Successful projects will result in new methods or techniques which will be disseminated to the UA research community via the core’s website, and be incorporated into the core’s standard operating procedures and capabilities.
2. The acquisition of preliminary data needed for extramural proposals. Successful projects will result in at least one new extramural research proposal. PIs must note the specific extramural funding opportunity announcement for which they plan to submit and their anticipated submission date along with their CFPP application. A full justification of the anticipated studies is required.
3. The technical training of students conducting research under existing extramural funding. Successful projects will result in student researchers with the technical skills to operate equipment safely, efficiently and independently within the core facility(ies). PIs should note the student(s) to be trained, the core(s) in which they will be trained, the equipment on which they are to be trained, and the funding source under which the student’s research project is funded. Proposals to train students from traditionally marginalized groups will be given funding priority.

For additional information and to apply, see Arizona Cultivate.

Description: The RII Core Facilities Pilot Program is designed to support three key types of activity within the RII-managed core facilities. Each CFPP proposal will be evaluated on scientific merit and feasibility, and should focus on one or more of the following activity types:

1. The development of new methods or techniques that would extend the standard operating procedures and capabilities of RII-managed core facilities and potentially impact multiple UA researchers. Successful projects will result in new methods or techniques which will be disseminated to the UA research community via the core’s website, and be incorporated into the core’s standard operating procedures and capabilities.
2. The acquisition of preliminary data needed for extramural proposals. Successful projects will result in at least one new extramural research proposal. PIs must note the specific extramural funding opportunity announcement for which they plan to submit and their anticipated submission date along with their CFPP application. A full justification of the anticipated studies is required.
3. The technical training of students conducting research under existing extramural funding. Successful projects will result in student researchers with the technical skills to operate equipment safely, efficiently and independently within the core facility(ies). PIs should note the student(s) to be trained, the core(s) in which they will be trained, the equipment on which they are to be trained, and the funding source under which the student’s research project is funded. Proposals to train students from traditionally marginalized groups will be given funding priority.

Due date: May 7, 2025 at 5pm
To apply, see Arizona Cultivate

Description: The RII Core Facilities Pilot Program is designed to support three key types of activity within the RII-managed core facilities. Each CFPP proposal will be evaluated on scientific merit and feasibility, and should focus on one or more of the following activity types:

1. The development of new methods or techniques that would extend the standard operating procedures and capabilities of RII-managed core facilities and potentially impact multiple UA researchers. Successful projects will result in new methods or techniques which will be disseminated to the UA research community via the core’s website, and be incorporated into the core’s standard operating procedures and capabilities.
2. The acquisition of preliminary data needed for extramural proposals. Successful projects will result in at least one new extramural research proposal. PIs must note the specific extramural funding opportunity announcement for which they plan to submit and their anticipated submission date along with their CFPP application. A full justification of the anticipated studies is required.
3. The technical training of students conducting research under existing extramural funding. Successful projects will result in student researchers with the technical skills to operate equipment safely, efficiently and independently within the core facility(ies). PIs should note the student(s) to be trained, the core(s) in which they will be trained, the equipment on which they are to be trained, and the funding source under which the student’s research project is funded. Proposals to train students from traditionally marginalized groups will be given funding priority.

Due date: February 5, 2025 at 5pm
To apply, see UA Cultivate

Description: The RII Core Facilities Pilot Program is designed to support three key types of activity within the RII-managed core facilities. Each CFPP proposal will be evaluated on scientific merit and feasibility, and should focus on one or more of the following activity types:

1. The development of new methods or techniques that would extend the standard operating procedures and capabilities of RII-managed core facilities and potentially impact multiple UA researchers. Successful projects will result in new methods or techniques which will be disseminated to the UA research community via the core’s website, and be incorporated into the core’s standard operating procedures and capabilities.
2. The acquisition of preliminary data needed for extramural proposals. Successful projects will result in at least one new extramural research proposal. PIs must note the specific extramural funding opportunity announcement for which they plan to submit and their anticipated submission date along with their CFPP application. A full justification of the anticipated studies is required.
3. The technical training of students conducting research under existing extramural funding. Successful projects will result in student researchers with the technical skills to operate equipment safely, efficiently and independently within the core facility(ies). PIs should note the student(s) to be trained, the core(s) in which they will be trained, the equipment on which they are to be trained, and the funding source under which the student’s research project is funded. Proposals to train students from traditionally marginalized groups will be given funding priority.

Due date: November 6, 2024 at 5pm

UA Cultivate link: https://azcultivate.arizona.edu/#competitionDetail/1952433

Description: The RII Core Facilities Pilot Program is designed to support three key types of activity within the RII-managed core facilities. Each CFPP proposal will be evaluated on scientific merit and feasibility, and should focus on one or more of the following activity types:

1. The development of new methods or techniques that would extend the standard operating procedures and capabilities of RII-managed core facilities and potentially impact multiple UA researchers. Successful projects will result in new methods or techniques which will be disseminated to the UA research community via the core’s website, and be incorporated into the core’s standard operating procedures and capabilities.
2. The acquisition of preliminary data needed for extramural proposals. Successful projects will result in at least one new extramural research proposal. PIs must note the specific extramural funding opportunity announcement for which they plan to submit and their anticipated submission date along with their CFPP application. A full justification of the anticipated studies is required.
3. The technical training of students conducting research under existing extramural funding. Successful projects will result in student researchers with the technical skills to operate equipment safely, efficiently and independently within the core facility(ies). PIs should note the student(s) to be trained, the core(s) in which they will be trained, the equipment on which they are to be trained, and the funding source under which the student’s research project is funded. Proposals to train students from traditionally marginalized groups will be given funding priority.

Due date: August 2, 2024 at 5pm

UA Cultivate link: https://azcultivate.arizona.edu/#competitionDetail/1943071

Learn how Multi-Omic Spatial Profiling can advance your research, now available at Flow Cytometry Immune Monitoring Shared Resource (FCIMSR).

Registration

AGENDA

11 am-Noon - CosMx Overview, Kaitlyn LaCourse, PhD, Field Applications Scientist at NanoString
                        Case Study, Yana Zavros, PhD, Director, Tissue Acquisition and 
                        Cellular/Molecular Analysis Shared Resouce,
                        Professor, Cellular & Molecular Medicine

Noon-12:15 pm - Lunch provided

12:15-12:45 pm - AtoMx Data Analysis Overview

12:45-1 pm - How to get your spatial project started

1:30-4:30 pm - CosMx One-on-One Project Discussions (Schedule your 30 minute consultation with NanoString today)